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Which of the following statement is INCO...

Which of the following statement is INCORRECT regarding actin filaments?

A

Each actin filament is made of two G actin

B

Each F actin is a polymer of G actin

C

Troponin is a complex protein distributed at regular intervals on tropomyosin

D

Tropomyosin run close to F -actin along its length

Text Solution

AI Generated Solution

The correct Answer is:
To determine which statement is INCORRECT regarding actin filaments, we will analyze the properties and components of actin filaments step by step. ### Step 1: Understanding Actin Filaments Actin filaments, also known as microfilaments, are one of the main components of the cytoskeleton in eukaryotic cells. They are primarily composed of actin, a globular protein that polymerizes to form long, thin fibers. **Hint:** Actin filaments are made of monomers called G-actin that polymerize to form F-actin. ### Step 2: Composition of Actin Filaments Actin filaments are formed from two strands of filamentous actin (F-actin), which are polymers of globular actin (G-actin). Each F-actin is made up of many G-actin monomers. **Hint:** Remember that F-actin is a polymer made from multiple G-actin units. ### Step 3: Role of Tropomyosin and Troponin Tropomyosin is a protein that runs along the length of the F-actin and helps regulate the interaction between actin and myosin. Troponin is a complex protein that binds to tropomyosin and actin, and it plays a crucial role in muscle contraction by regulating the exposure of the myosin-binding sites on actin. **Hint:** Tropomyosin and troponin are regulatory proteins associated with actin filaments. ### Step 4: Evaluating the Statements Now, we will evaluate the provided statements regarding actin filaments to identify the incorrect one: 1. **Each actin filament is made up of two G-actin.** - This statement is INCORRECT because each actin filament is made up of two F-actin strands, which are themselves composed of many G-actin monomers. 2. **Troponin is a complex protein distributed at regular intervals on the tropomyosin.** - This statement is CORRECT. 3. **Tropomyosin runs close to the F-actin along its length.** - This statement is also CORRECT. ### Step 5: Conclusion Based on the evaluation, the INCORRECT statement regarding actin filaments is the first one: "Each actin filament is made up of two G-actin." **Final Answer:** The incorrect statement is: "Each actin filament is made up of two G-actin."
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