Which of the following events are not associated with the phase /cycle of malarial parasite in man ?

Options

A. Entry of parasite into hepatocytes
B. Formation of motile zygote
C. Formation of gametocytes
D. Erythrocytic schizogony

Answer

To solve the question regarding which events are not associated with the phase/cycle of the malarial parasite in humans, we will analyze each option provided:

1. **Entry of parasites into hepatocytes**:
- The first step in the life cycle of the malaria parasite (Plasmodium) involves the entry of sporozoites into the liver cells (hepatocytes) after a mosquito bite. This event is indeed associated with the malarial cycle in humans.

2. **Formation of motile zygote**:
- In the life cycle of the malaria parasite, the zygote formed after fertilization of male and female gametes is actually non-motile. It develops into an ookinete, which then becomes motile. Therefore, the formation of a motile zygote is not an event that occurs in the human phase of the malaria life cycle.

3. **Formation of gametocytes**:
- Gametocytes are the sexual forms of the malaria parasite that develop in the human host. These gametocytes are crucial for the continuation of the life cycle as they are taken up by mosquitoes during a blood meal. Thus, this event is associated with the malarial cycle in humans.

4. **Erythrocytic schizogamy**:
- This refers to the asexual reproduction of the malaria parasite within red blood cells (erythrocytes). It is a key part of the malaria life cycle in humans, leading to the release of merozoites that can infect more red blood cells. Therefore, this event is also associated with the malarial cycle in humans.

Based on the analysis above, the event that is **not associated** with the phase/cycle of the malarial parasite in humans is:

**Answer: Formation of motile zygote (Option B)**