Malonate is inhibited by succinate dehydrogenase. This is a type of

Options

A. non-competitive inhibition
B. competitive inhibition
C. negative feed back
D. allosteric inhibition

Answer

To solve the question "Malonate is inhibited by succinate dehydrogenase. This is a type of:", we will analyze the information provided step by step.

### Step 1: Understand the Role of Succinate Dehydrogenase
Succinate dehydrogenase is an enzyme that catalyzes the conversion of succinate to fumarate in the citric acid cycle. Enzymes are biological catalysts that speed up reactions.

**Hint**: Remember that enzymes have specific substrates they act upon.

### Step 2: Identify the Inhibitor
Malonate is mentioned as an inhibitor of succinate dehydrogenase. It is important to note that malonate is structurally similar to succinate, the substrate for succinate dehydrogenase.

**Hint**: Look for structural similarities between the inhibitor and the substrate.

### Step 3: Determine the Type of Inhibition
Since malonate is structurally similar to succinate, it can compete with succinate for the active site of the enzyme. This is the hallmark of competitive inhibition, where the inhibitor competes with the substrate for binding to the active site.

**Hint**: Think about how inhibitors can affect the binding of substrates to enzymes.

### Step 4: Eliminate Other Options
- **Non-competitive inhibition**: The inhibitor can bind to the enzyme regardless of whether the substrate is bound, which is not the case here.
- **Negative feedback**: This involves a product inhibiting an enzyme that produced it, which is not relevant to this scenario.
- **Allosteric inhibition**: This involves an inhibitor binding to a site other than the active site, which is also not applicable here.

**Hint**: Consider the definitions of each type of inhibition and how they apply to the situation.

### Conclusion
Based on the analysis, the correct answer is that malonate inhibiting succinate dehydrogenase is an example of **competitive inhibition**.

**Final Answer**: Competitive inhibition.

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