Disease caused by undersecretion of adrenal cortex

Options

A. Sterility
B. Cretinism
C. Cushing disease
D. Addison's disease

Answer

### Step-by-Step Solution:

1. **Understanding the Question**: The question asks for the disease caused by the undersecretion of the adrenal cortex. The adrenal cortex is responsible for producing several hormones, including cortisol and aldosterone.

2. **Analyzing the Options**:
- **Option 1: Sterility**: This condition refers to the inability to produce offspring and is not related to adrenal cortex function.
- **Option 2: Cretinism**: This is caused by a deficiency of thyroid hormones, particularly in newborns, and is not related to adrenal cortex function.
- **Option 3: Cushing Disease**: This condition is associated with an overproduction of cortisol from the adrenal cortex, not undersecretion.
- **Option 4: Addison's Disease**: This disease is characterized by the undersecretion of adrenal hormones, particularly cortisol and sometimes aldosterone.

3. **Identifying the Correct Answer**: Based on the analysis, Addison's disease is the only option that corresponds to the undersecretion of the adrenal cortex. It is also known as adrenal insufficiency.

4. **Conclusion**: The disease caused by the undersecretion of the adrenal cortex is **Addison's Disease**.