Read the following statement and select the incorrect one amongst the following.

Options

A. `T_4` is the chief circulating form of throid hormone, but is less active than `T_3`
B. Acromegaly is usually associated with hypoglycemia and hypotension
C. Thyroxine promotes the body growth and metamorphosis in amphibians
D. Hypothalamus produces the hormone concerned with milk ejection.

Answer

To solve the question of identifying the incorrect statement regarding thyroid hormones and related physiological processes, we will analyze each statement one by one.

### Step-by-Step Solution:

1. **Statement A: T4 is the chief circulating form of thyroid hormone but is less active than T3.**
- **Analysis:** This statement is correct. T4 (thyroxine) is indeed the primary form of thyroid hormone found in circulation, while T3 (triiodothyronine) is more biologically active. T4 is converted into T3 in various tissues, but T4 itself has lower activity compared to T3.

2. **Statement B: Acromegaly is usually associated with hypoglycemia and hypotension.**
- **Analysis:** This statement is incorrect. Acromegaly is caused by the overproduction of growth hormone, typically due to a pituitary tumor. This leads to increased blood glucose levels (hyperglycemia) as growth hormone stimulates gluconeogenesis in the liver. Therefore, acromegaly is associated with hyperglycemia, not hypoglycemia, and it can also lead to hypertension rather than hypotension.

3. **Statement C: Thyroxin promotes body growth and metamorphosis in amphibians.**
- **Analysis:** This statement is correct. Thyroxin (T4) plays a crucial role in the growth and development of amphibians, particularly during the metamorphosis from larva to adult form, such as in frogs.

4. **Statement D: Hypothalamus produces the hormone concerned with milk ejection.**
- **Analysis:** This statement is also correct. The hormone responsible for milk ejection is oxytocin, which is synthesized in the hypothalamus and then stored and released from the posterior pituitary gland.

### Conclusion:
The incorrect statement among the options provided is **Statement B**: "Acromegaly is usually associated with hypoglycemia and hypotension."