How many nucleotides are used for the synthesis of A chain and B chain of insulin?

Options

A. 90 for A and 63 for B
B. 63 for A and 90 for B
C. 92 for A and 61 for B
D. 60 for A and 61 for B

Answer

To determine how many nucleotides are used for the synthesis of the A chain and B chain of insulin, we can break down the information as follows:

1. **Understanding Insulin Structure**:
- Insulin is a peptide hormone composed of two chains: the A chain and the B chain.

2. **Nucleotide Count for A Chain**:
- The A chain of insulin consists of **63 nucleotides**.
- It is important to note that the A chain is made up of **21 amino acids**, but for our purpose, we are focusing on the nucleotide count.

3. **Nucleotide Count for B Chain**:
- The B chain of insulin consists of **90 nucleotides**.
- Similarly, the B chain is made up of **30 amino acids**, but again, we focus on the nucleotide count.

4. **Total Nucleotide Count**:
- To find the total number of nucleotides used for both chains, we simply add the nucleotides from both chains:
- Total nucleotides = Nucleotides in A chain + Nucleotides in B chain
- Total nucleotides = 63 (A chain) + 90 (B chain) = **153 nucleotides**.

5. **Conclusion**:
- Therefore, the total number of nucleotides used for the synthesis of the A chain and B chain of insulin is **153 nucleotides**.