Select the false statement from the following.

Options

A. Genetic engineering includes techniques to alter chemistry of genetic material (DNA and RNA).
B. Sexual reproduction is more advantageous than asexual reproduction.
C. Genetic engineering allows us to introduce desirable set of genes without the undesirable gene into the target organism.
D. Plasmid is autonomously replicating linear extra chromosomal DNA.

Answer

To solve the question, we will analyze each statement provided and determine which one is false.

### Step-by-Step Solution:

1. **Analyze Statement 1**:
- **Statement**: "Genetic engineering includes techniques to alter the chemistry of genetic material that is DNA and RNA."
- **Evaluation**: This statement is true. Genetic engineering indeed involves manipulating DNA and RNA to change the genetic makeup of organisms.

2. **Analyze Statement 2**:
- **Statement**: "Sexual reproduction is more advantageous than asexual reproduction."
- **Evaluation**: This statement is also true. Sexual reproduction promotes genetic variation, which can enhance survival and adaptability in changing environments.

3. **Analyze Statement 3**:
- **Statement**: "Genetic engineering allows us to introduce a desirable set of genes without the undesirable gene into the target organism."
- **Evaluation**: This statement is true as well. Modern genetic engineering techniques allow for the precise introduction of specific genes while excluding unwanted genes.

4. **Analyze Statement 4**:
- **Statement**: "Plasmid is autonomously replicating linear extra-chromosomal DNA."
- **Evaluation**: This statement is false. While plasmids are indeed autonomously replicating and extra-chromosomal, they are typically circular, not linear.

### Conclusion:
The false statement among the options provided is **Statement 4**.

### Final Answer:
**Option D**: "Plasmid is autonomously replicating linear extra-chromosomal DNA." (This statement is false because plasmids are circular, not linear.)

---