Which of the following is a wrong match with respect to transcription ?

Options

A. Rho factor - Terminates transcription
B. AUG - Initiator codon
C. Sigma factor - Initiates transcription
D. All of these

Answer

To solve the question "Which of the following is a wrong match with respect to transcription?", we will follow these steps:

### Step 1: Understand the Process of Transcription
Transcription is the process by which a segment of DNA is copied into RNA, specifically mRNA, by the enzyme RNA polymerase. This process involves three main stages: initiation, elongation, and termination.

### Step 2: Identify Key Components of Transcription
- **RNA Polymerase**: The enzyme responsible for synthesizing RNA from the DNA template.
- **Sigma Factor**: A protein that helps RNA polymerase to initiate transcription by binding to the promoter region of the DNA.
- **Rho Factor**: A protein involved in the termination of transcription in prokaryotes.

### Step 3: Analyze Each Option
1. **Rho factor terminates transcription**: This statement is correct. The Rho factor is indeed involved in the termination of transcription in prokaryotes.

2. **Sigma factor initiates transcription**: This statement is also correct. The sigma factor is essential for the initiation of transcription as it helps RNA polymerase bind to the promoter.

3. **AUG is an initiator codon**: This statement is correct in the context of translation, where AUG serves as the start codon for protein synthesis. However, it is not directly related to the transcription process itself, as transcription involves the synthesis of RNA from DNA, and the codon is a feature of the mRNA produced after transcription.

### Step 4: Determine the Wrong Match
Among the options analyzed, the third statement about AUG being an initiator codon is misleading in the context of transcription. While it is true that AUG is an initiator codon, it does not pertain to the transcription process itself, which is the focus of the question.

### Conclusion
The wrong match with respect to transcription is the statement regarding AUG as an initiator codon.

### Final Answer
The correct answer is that the statement "AUG is an initiator codon" is a wrong match with respect to transcription.

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