Find the INCORRECT match.

Options

A. PCR - amplification of the gene of interest.
B. Cloning - Ability to form large number of copies of the recombinant DNA in the host cell like E. coli.
C. Restriction enzymes - Molecular scissors
D. Exonucleases - Molecular glue

Answer

To determine the incorrect match from the given options, we will analyze each option one by one.

### Step-by-Step Solution:

1. **Option A: PCR amplification of the gene of interest**
- **Explanation**: PCR stands for Polymerase Chain Reaction. It is a technique used to amplify specific segments of DNA, making millions of copies of a particular gene of interest. This option is correct.

2. **Option B: Cloning ability to form large number of copies of the recombinant DNA in the host**
- **Explanation**: Cloning involves inserting recombinant DNA into a host organism, which then replicates the DNA, allowing for the production of many copies. This statement is also correct.

3. **Option C: Restriction enzymes molecular scissors**
- **Explanation**: Restriction enzymes are indeed known as molecular scissors because they cut DNA at specific sequences. This option is correct as well.

4. **Option D: Exonucleases molecular glue**
- **Explanation**: Exonucleases are enzymes that remove nucleotides from the ends of a DNA molecule. They do not act as molecular glue. The term "molecular glue" is more accurately associated with DNA ligase, which joins DNA fragments together. Therefore, this option is incorrect.

### Conclusion:
The incorrect match is **Option D: Exonucleases molecular glue**.