If a person is suffering from severe male infertility due to very few sperms (oligospermia) in the ejaculate , it can be overcome by the use of …………

Options

A. GIFT
B. ZIFT
C. ICSI
D. Both (B) and (C)

Answer

To solve the question regarding how to overcome severe male infertility due to oligospermia, we will analyze the options provided and determine the most suitable method.

### Step-by-Step Solution:

1. **Understanding Oligospermia**:
- Oligospermia refers to a condition where a male has a low sperm count in his ejaculate. This condition can lead to difficulties in achieving pregnancy.

**Hint**: Remember that oligospermia is characterized by a low number of sperm in the ejaculate.

2. **Evaluating the Options**:
- **Option 1: GIFT (Gamete Intra-Fallopian Transfer)**: This method involves placing both eggs and sperm directly into the fallopian tubes. It may not be suitable for cases of oligospermia since it requires a sufficient number of sperm.

**Hint**: GIFT requires both eggs and sperm to be viable and sufficient in quantity.

- **Option 2: ZIFT (Zygote Intra-Fallopian Transfer)**: This technique involves fertilizing the egg in the lab and then transferring the zygote into the fallopian tubes. Similar to GIFT, it may not be ideal for oligospermia due to the need for a viable sperm count.

**Hint**: ZIFT also relies on having enough sperm to fertilize the egg before transfer.

- **Option 3: ICSI (Intracytoplasmic Sperm Injection)**: This is a specialized form of in vitro fertilization where a single sperm is injected directly into a mature egg. This method is specifically designed to address cases of male infertility, including oligospermia, as it does not require a large number of sperm.

**Hint**: ICSI is particularly useful for severe male factor infertility since it only needs one sperm.

- **Option 4: Both B and C**: This option suggests that both ZIFT and ICSI can be used to overcome oligospermia. However, since ZIFT may not be effective for low sperm counts, this option is not correct.

3. **Conclusion**:
- After evaluating all options, the most effective method for overcoming severe male infertility due to oligospermia is **Option 3: ICSI**.

**Final Answer**: The correct answer is **ICSI (Intracytoplasmic Sperm Injection)**.