Which of the following shows point matution?

Options

A. Alteration in DNA sequence
B. Deletion of segment of DNA
C. Change in a single base pair of DNA
D. Gain of a segment of DNA

Answer

To solve the question "Which of the following shows point mutation?", we need to analyze the provided options and understand what point mutation entails.

### Step-by-Step Solution:

1. **Understanding Mutation**:
- A mutation is defined as a sudden change in the DNA sequence. This can occur in various forms, but we are specifically looking for point mutations.

2. **Defining Point Mutation**:
- Point mutation refers to a change that occurs at a specific point in the DNA sequence. This typically involves the alteration of a single base pair.

3. **Analyzing the Options**:
- **Option A**: Alteration in DNA sequence - This is too broad and could refer to various types of mutations, not specifically point mutations.
- **Option B**: Deletion of a segment of DNA - This refers to a frameshift mutation, which involves removing a larger segment of DNA, thus altering the reading frame.
- **Option C**: Change in a single base pair of DNA - This directly describes a point mutation, as it involves a change at a specific point in the DNA sequence.
- **Option D**: Gain of a segment of DNA - Similar to deletion, this also refers to a frameshift mutation, which adds to the DNA sequence.

4. **Identifying the Correct Answer**:
- Among the options, **Option C** (Change in a single base pair of DNA) is the only one that accurately describes a point mutation.

### Final Answer:
The correct option that shows point mutation is **C: Change in a single base pair of DNA**.

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