In prophase I, the stage that closely resembles prometaphase of mitosis is :

Options

A. Diplotene
B. Chaismata
C. Leptotene
D. Diakinesis

Answer

To solve the question regarding which stage of prophase I closely resembles prometaphase of mitosis, we can follow these steps:

### Step-by-Step Solution

1. **Understand the Context**: The question is about prophase I of meiosis, which is different from prophase in mitosis. Prophase I has several sub-stages.

2. **Identify the Sub-stages of Prophase I**: The sub-stages of prophase I are:
- Leptotene
- Zygotene
- Pachytene
- Diplotene
- Diakinesis

3. **Recall the Characteristics of Prometaphase in Mitosis**: In prometaphase of mitosis, the nuclear envelope breaks down, and spindle fibers attach to the chromosomes, preparing them for alignment at the metaphase plate.

4. **Analyze Each Sub-stage of Prophase I**:
- **Leptotene**: Chromosomes condense, and the nuclear membrane begins to break down.
- **Zygotene**: Homologous chromosomes pair up (synapsis).
- **Pachytene**: Crossing over occurs between homologous chromosomes.
- **Diplotene**: Homologous chromosomes begin to separate but remain connected at chiasmata.
- **Diakinesis**: Chromosomes condense further, and the nuclear envelope completely breaks down, preparing for metaphase.

5. **Determine Which Stage Resembles Prometaphase**:
- Diakinesis is the stage where the cell prepares for metaphase, with the nuclear envelope fully dissolved and spindle fibers starting to attach to the chromosomes. This is similar to the prometaphase of mitosis, where the spindle apparatus is fully formed and chromosomes are aligned for separation.

6. **Select the Correct Answer**: Based on the analysis, the stage of prophase I that closely resembles prometaphase of mitosis is **Diakinesis**.

### Final Answer
**D. Diakinesis**