Which hormone acts on Sertoli cells?

Options

A. LH
B. FSH
C. Inhibin
D. Testosterone

Answer

To determine which hormone acts on Sertoli cells, we can follow these steps:

### Step-by-Step Solution:

1. **Understand Sertoli Cells**: Sertoli cells are specialized cells located in the seminiferous tubules of the testes. They play a crucial role in supporting and nourishing developing sperm cells during spermatogenesis.

2. **Identify the Hormones**: The options given are:
- LH (Luteinizing Hormone)
- FSH (Follicle Stimulating Hormone)
- Inhibin
- Testosterone

3. **Research the Function of Each Hormone**:
- **LH**: Primarily stimulates Leydig cells to produce testosterone.
- **FSH**: Stimulates Sertoli cells to support sperm production and maturation.
- **Inhibin**: Produced by Sertoli cells, it regulates FSH secretion but does not act on Sertoli cells.
- **Testosterone**: Primarily acts on Leydig cells and has various effects on male secondary sexual characteristics, but it does not directly stimulate Sertoli cells.

4. **Determine the Correct Hormone**: Based on the functions identified, FSH is the hormone that specifically acts on Sertoli cells to promote their function in sperm development.

5. **Conclusion**: The hormone that acts on Sertoli cells is FSH (Follicle Stimulating Hormone).

### Final Answer:
The hormone that acts on Sertoli cells is **FSH (Follicle Stimulating Hormone)**.

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