Which set of hormones is steroidal in nature?

Options

A. Cortisol and estradiol
B. Insulin and glucagon
C. Adrenaline and non-adrenaline
D. Thyroxine and calcitonin

Answer

To determine which set of hormones is steroidal in nature, we need to analyze each option provided in the question.

### Step-by-Step Solution:

1. **Understand Hormone Classification**:
- Hormones can be classified into different categories based on their chemical structure, primarily into peptide hormones and steroid hormones.
- Peptide hormones are made of amino acids, while steroid hormones are derived from cholesterol.

2. **Evaluate Each Option**:
- **Option A: Cortisol and Estradiol**:
- Cortisol is a glucocorticoid hormone produced by the adrenal cortex and is steroidal in nature.
- Estradiol is an estrogen hormone also produced by the ovaries (and adrenal glands) and is steroidal.
- **Conclusion**: Both are steroid hormones.

- **Option B: Insulin and Glucagon**:
- Insulin and glucagon are both peptide hormones produced by the pancreas.
- **Conclusion**: Neither is steroidal.

- **Option C: Adrenaline and Noradrenaline**:
- These hormones are produced by the adrenal medulla and are derived from amino acids (specifically tyrosine).
- **Conclusion**: Neither is steroidal.

- **Option D: Thyroxine and Calcitonin**:
- Thyroxine (T4) is produced by the thyroid gland and is an amino acid derivative.
- Calcitonin is also a peptide hormone produced by the thyroid gland.
- **Conclusion**: Neither is steroidal.

3. **Final Answer**:
- After evaluating all options, the only pair of hormones that are steroidal in nature is **Option A: Cortisol and Estradiol**.