Select the incorrect statement about DNA.

Options

A. DNA is acidic in nature due to presence of phosphate group.
B. DNA act as genetic material in majority of the organisms an it is structurally more stable as compared to RNA.
C. In bacteriophage `lambda`, 48502 base pairs are found in DNA.
D. F. Meischer first identified the DNA in 1829.

Answer

To solve the question "Select the incorrect statement about DNA," we will analyze each statement provided in the context of DNA's properties and history.

### Step-by-Step Solution:

1. **Statement Analysis**:
- **Statement 1**: "DNA is acidic in nature due to the presence of the phosphate group."
- **Analysis**: This statement is correct. DNA is indeed acidic because of the phosphate groups in its backbone, which can release protons (H⁺) in solution, contributing to its acidic nature.

2. **Statement 2**: "DNA acts as genetic material in the majority of organisms as it is structurally more stable compared to RNA."
- **Analysis**: This statement is also correct. DNA is more stable than RNA due to its double-stranded structure and the presence of deoxyribose sugar, which lacks an oxygen atom at the second carbon compared to ribose in RNA. This structural difference makes DNA less prone to hydrolysis.

3. **Statement 3**: "In bacteriophage lambda, 48502 base pairs are found in DNA."
- **Analysis**: This statement is correct. Bacteriophage lambda does indeed have approximately 48,502 base pairs in its DNA.

4. **Statement 4**: "Frederick Mischer first identified the DNA in 1829."
- **Analysis**: This statement is incorrect. Frederick Mischer actually identified DNA in 1869, not 1829. He discovered an acidic substance in the nucleus and termed it "nuclein."

### Conclusion:
The incorrect statement about DNA is **Statement 4**.