Which statement is correct about the disorder of skeletal or muscular system?

Options

A. Muscular dystrophy - Age - related shroteining of muscles
B. Osteoporosis - Decrease in bone mass and a higher chance of fractures with advancing age
C. Myasthenia gravis - Autommue disorder which inhibits sliding of myosin filaments
D. Gout - inflammation of joints due to extra deposition of calcium

Answer

To determine which statement is correct about the disorders of the skeletal or muscular system, we will analyze each option provided in the question.

### Step-by-Step Solution:

1. **Muscular Dystrophy**:
- Muscular dystrophy is a group of inherited genetic disorders characterized by progressive weakness and breakdown of skeletal muscles.
- It is caused by mutations, which can be X-linked or autosomal (dominant or recessive).
- **Conclusion**: The statement about muscular dystrophy being age-related shortening of muscles is incorrect.

2. **Osteoporosis**:
- Osteoporosis is a condition that is primarily related to aging, where there is a decrease in bone mass and an increased risk of fractures.
- As people age, calcium is lost from the bones, leading to decreased bone density and making bones more fragile.
- **Conclusion**: The statement about osteoporosis indicating a decrease in bone mass and higher chances of fractures with advancing age is correct.

3. **Myasthenia Gravis**:
- Myasthenia gravis is an autoimmune disorder where antibodies block or destroy acetylcholine receptors at the neuromuscular junction.
- This results in muscle weakness and fatigue but does not inhibit the sliding of myosin filaments directly.
- **Conclusion**: The statement regarding myasthenia gravis inhibiting sliding of myosin filaments is incorrect.

4. **Gout**:
- Gout is characterized by inflammation of the joints due to the deposition of uric acid crystals, not calcium.
- It leads to painful swelling and inflammation in the affected joints.
- **Conclusion**: The statement about gout being due to calcium deposition is incorrect.

### Final Answer:
The correct statement about the disorder of the skeletal or muscular system is related to **osteoporosis**, which states that there is a decrease in bone mass and higher chances of fractures with advancing age.

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