The correct sequence of involvement of cell organelles in secretion of proteins from the cell is

Options

A. Nucleus `to` Endoplasmic reticulum `to` Ribosomes `to`Golgi apparatus `to`Secretory vesicles `to` Plasma membrane
B. Nucleus `to` Ribosomes `to` Endoplasmic reticulum `to` Golgi apparatus `to` Secretory vesicles `to`Plasma membrane
C. Nucleus `to`Ribosomes `to`Endopiasmic reticulum `to`Lysosomes `to`Plasma membrane
D. Nucleus `to` Endoplasmic reticulum `to` Ribosones `to` Golgi apparatus`to` Lysosomes`to` Plasma membrane

Answer

To determine the correct sequence of involvement of cell organelles in the secretion of proteins from the cell, we can break down the process step by step:

### Step-by-Step Solution:

1. **Nucleus**: The process begins in the nucleus, where the genetic information (DNA) is transcribed into messenger RNA (mRNA). This mRNA carries the instructions for protein synthesis.

**Hint**: Think of the nucleus as the control center where the blueprint for proteins is created.

2. **Ribosome**: The mRNA then travels from the nucleus to the ribosomes, which can be found either free in the cytoplasm or attached to the rough endoplasmic reticulum (RER). Ribosomes are the sites of protein synthesis, where the mRNA is translated into a polypeptide chain (protein).

**Hint**: Ribosomes are like factories where the actual assembly of proteins takes place.

3. **Endoplasmic Reticulum (ER)**: After synthesis, the newly formed protein enters the rough endoplasmic reticulum (RER) for folding and modifications. The RER is studded with ribosomes, which is why it is "rough."

**Hint**: The ER acts as a conveyor belt, transporting proteins to the next stage after they are made.

4. **Golgi Apparatus**: The proteins then move to the Golgi apparatus, where they undergo further modifications, sorting, and packaging into vesicles. The Golgi apparatus is crucial for processing and preparing proteins for secretion.

**Hint**: Think of the Golgi apparatus as the post office of the cell, packaging and labeling proteins for delivery.

5. **Secretory Vesicles**: After processing in the Golgi apparatus, the proteins are enclosed in secretory vesicles. These vesicles transport the proteins to the plasma membrane.

**Hint**: Secretory vesicles are like delivery trucks that carry the packaged proteins to their destination.

6. **Plasma Membrane**: Finally, the secretory vesicles fuse with the plasma membrane, releasing the proteins outside the cell through a process called exocytosis.

**Hint**: The plasma membrane is the cell's outer barrier, and it plays a key role in exporting the finished proteins.

### Final Sequence:
The correct sequence of involvement of cell organelles in the secretion of proteins from the cell is:
1. Nucleus
2. Ribosome
3. Endoplasmic Reticulum
4. Golgi Apparatus
5. Secretory Vesicles
6. Plasma Membrane

### Conclusion:
Thus, the correct answer is the sequence: Nucleus → Ribosome → Endoplasmic Reticulum → Golgi Apparatus → Secretory Vesicles → Plasma Membrane.