Which of these statements is incorrect?

Options

A. Enzymes of TCA cycle are present in mitochondrial matrix
B. Glycolysis occurs in cytosol
C. Glycolysis operates as long as it is supplied with NAD that can pick up hydrogen atoms
D. Oxidative phosphorylation takes place in outer mitochondrial membrane

Answer

To determine which statement is incorrect, we will analyze each option one by one.

### Step-by-Step Solution:

1. **Evaluate Option 1: "Enzymes of TCA cycle are present in mitochondrial matrix."**
- The TCA cycle, also known as the Krebs cycle, occurs in the mitochondrial matrix. Therefore, this statement is correct.

2. **Evaluate Option 2: "Glycolysis occurs in cytosol."**
- Glycolysis is the process of breaking down glucose into pyruvate and occurs in the cytosol (the fluid part of the cytoplasm). Thus, this statement is also correct.

3. **Evaluate Option 3: "Glycolysis operates as long as it is supplied with NAD that can pick up hydrogen atoms."**
- Glycolysis requires NAD+ to accept hydrogen atoms and convert into NADH. As long as NAD+ is available, glycolysis can continue. Therefore, this statement is correct as well.

4. **Evaluate Option 4: "Oxidative Phosphorylation takes place in outer mitochondrial membrane."**
- Oxidative phosphorylation actually occurs in the inner mitochondrial membrane, not the outer membrane. This statement is incorrect.

### Conclusion:
The incorrect statement is **Option 4: "Oxidative Phosphorylation takes place in outer mitochondrial membrane."**

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