Diabets insipidus is caused due to :

Options

A. Hypersecretion of vasopressin
B. Hypersecretion of insulin
C. Hyposecretion of insulin
D. Hyposecretion of vasopressin

Answer

### Step-by-Step Solution:

1. **Understanding Diabetes Insipidus**:
- Diabetes insipidus is a condition characterized by excessive thirst and the excretion of large amounts of dilute urine. It is primarily related to the hormone vasopressin (also known as antidiuretic hormone, ADH).

2. **Role of Vasopressin**:
- Vasopressin is produced in the hypothalamus and stored in the posterior pituitary gland. It plays a crucial role in regulating water balance in the body by promoting water reabsorption in the kidneys.

3. **Causes of Diabetes Insipidus**:
- Diabetes insipidus can occur due to insufficient production of vasopressin (hyposecretion) or the kidneys' inability to respond to vasopressin (nephrogenic diabetes insipidus).

4. **Evaluating the Options**:
- The question asks about the cause of diabetes insipidus, and the options provided include:
- A) Hypersecretion of vasopressin
- B) Hyposecretion of vasopressin
- C) Normal secretion of vasopressin
- D) Inability of the kidneys to respond to vasopressin

5. **Identifying the Correct Answer**:
- Since diabetes insipidus is primarily caused by a lack of vasopressin (hyposecretion) or the kidneys' inability to respond to it, the correct answer is **B) Hyposecretion of vasopressin**. This indicates that there is less vasopressin available to help the kidneys retain water.