Which type of bonding facilitates the action ligases?
a) Glycosidic bonding
b) Peptide bonding
c) H-bonding
d) Vander - waal force of attraction

Options

A. Glycosidic bonding
B. Peptide bonding
C. H-bonding
D. Vander - waal force of attraction

Answer

To determine which type of bonding facilitates the action of ligases, let's analyze each option step by step:

1. **Understanding Ligases**: Ligases are enzymes that facilitate the joining of two molecules by forming a bond between them. They are particularly important in DNA replication and repair.

2. **Analyzing the Options**:
- **a) Glycosidic bonding**: This type of bond is found between a sugar and a nitrogenous base in nucleotides. It is not directly involved in the action of ligases.
- **b) Peptide bonding**: Peptide bonds are formed between amino acids in proteins. This is unrelated to the action of ligases, which deal with nucleic acids.
- **c) H-bonding**: Hydrogen bonds are crucial in stabilizing the double-stranded structure of DNA. They occur between complementary base pairs (A-T and G-C) and are involved in the process of ligation as they help in aligning the DNA strands.
- **d) Van der Waals force of attraction**: These forces provide minor stability to the DNA structure but do not play a significant role in the action of ligases.

3. **Conclusion**: Among the options, hydrogen bonding is the most relevant to the action of ligases, as it helps in stabilizing the DNA strands during the ligation process. Therefore, the correct answer is **c) H-bonding**.

**Final Answer**: c) H-bonding

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