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Sickle cell anaemia is due to substituti...

Sickle cell anaemia is due to substitution/transversion (point mutation) in which

A

instead of glutamic acid, valine comes at number 6th position in one of `beta` chain of Hb

B

instead of valine, glutanic acid is inserted at number 6th position of `beta`-chain of Hb

C

valine is inserted at number 6th position in `alpha` chain of Hb

D

glutamic acid is substituted by valine at number 6th position of `alpha`-chain of Hb

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The correct Answer is:
A
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Sickle-cell anemia is caused due to the substitution of : 1. Valine by glutamic acid at sixth position of alpha chain of heamoglobin 2. Valine by glutamic acid at sixth position of beta chain of haemoglobin 3. glutamic acid by valine at sixth position of alpha chain of haemoglobin 4. glutamic acid by valine at sixth position of beta chain of haemoglobin

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