Read the following statements and choose the correct option.
I Failure of segregation of chromatids during cell division results in aneuploidy.
II. Chromosomal disorders are mainly determined by alteration or mutation in a single gene.
III. Thalassemia and cystic fibrosis are Mendelian disorders.
IV. Sickle cell anaemia is a X-linked trait.
V. Haemophilia is an autosome linked recessive disease.

Options

A. I and III alone are correct
B. I, III and IV alone are correct
C. III and IV alone are correct
D. II and IV alone are correct

Answer

A

Explanation

• Mendelian disorders are mainly determined by alteration or mutation in a single gene.
• Sickle cell anaemia is an autosome-linked trait.
• Haemophilia is an X-linked recessive disease.