Home
Class 12
BIOLOGY
Assertion: Hb^(S) Hb^(S) is homozygous c...

Assertion: `Hb^(S) Hb^(S)` is homozygous condition of sickle cell anaemia.
Reason: It occurs due to substitution of glutamic acid by valine at sixth position in `beta`-chain of haemoglobin.

A

If both assertion and reason are true and reason is the correct explanation of assertion.

B

If both assertion and reason are true but reason is not the correct explanation of assertion.

C

If assertion is true but reason is false

D

If both assertion and reason are false.

Text Solution

AI Generated Solution

Promotional Banner

Similar Questions

Explore conceptually related problems

Read the following statement s and choose the correct option In phenylketonuria the affected person does not secrete the enzyme to convert phenylalanine to tyrosine (II)Possibility of male becoming haemophiliac is extremely rare (III) Sickle cell anaemia is caused by the substitution of glutamic acid by valine at fifth position of beta chain of haemoglobin (IV) Myotonic dystrophy is an autosomal dominant trait

The defect sickle-cell anaemia is caused by the "_____" of glutamic acid by the valine at the 6^(th) position of the "_____" globin chain of the haemoglobin molecule.

Assertion :-Sickle-cell anaemia is caused by the substitution of glutamic acid by valine at the sixth position of the beta globin chain of the hemoglobin moecule. Reason :- It is due to the single base substitution at the sixth codon of the beta globin gene from GUG to GAG.

In sickle cell anaemia, the sequence of amino acid from first to seventh position of beta -chain of haemoglobin S (HbS) is

In sickle - cell anaemia , the defect is caused by the substitution of ……..(i) ……….by ………(ii) ………..in the ………(iii)………position of the beta - globin chain of the haemoglobin molecule.

Hb^(A) and Hb^(S) alleles of normal and sickle cell haemoblobin are

Sickle-cell anaemia is caused by a substitution mutation. At this sixth position of haemoglobin, ………... due to this mutation

A : Sickel cell anemia occurs due to the point mutation. R : mRNA produced from Hb(s) gene has GAG instead of GUG.

In sickle cell anaemia glutamic acid is replaced by valine Which one of the following triplets codes for valine ?