Select the wrong pair

Options

A. RNA polymerase I- Sn RNA 5S rRNA
B. RNA polymerase I- r-RNA
C. RNA polymerase II -hnRNA
D. RNA polymerase III – tRNA

Answer

To solve the question of selecting the wrong pair of RNA polymerases and their corresponding RNA types, we can follow these steps:

### Step 1: Identify the RNA Polymerases
In eukaryotes, there are three main types of RNA polymerases:
- **RNA Polymerase I (Pol I)**
- **RNA Polymerase II (Pol II)**
- **RNA Polymerase III (Pol III)**

### Step 2: Determine What Each Polymerase Synthesizes
- **RNA Polymerase I (Pol I)**: Synthesizes ribosomal RNA (rRNA), specifically the 28S, 18S, and 5.8S rRNA.
- **RNA Polymerase II (Pol II)**: Synthesizes messenger RNA (mRNA) and small nuclear RNA (snRNA).
- **RNA Polymerase III (Pol III)**: Synthesizes transfer RNA (tRNA) and 5S ribosomal RNA (5S rRNA).

### Step 3: Analyze Each Given Pair
Now, let's analyze the pairs provided in the question:
1. **RNA Polymerase I - Small Nuclear RNA**: This is incorrect because small nuclear RNA is synthesized by RNA Polymerase II.
2. **RNA Polymerase I - Ribosomal RNA**: This is correct as Pol I synthesizes rRNA.
3. **RNA Polymerase II - Heteronuclear RNA**: This is correct since heteronuclear RNA (hnRNA) refers to the precursor mRNA synthesized by Pol II.
4. **RNA Polymerase III - Transfer RNA**: This is correct as Pol III synthesizes tRNA.

### Step 4: Identify the Wrong Pair
From the analysis, the only incorrect pair is:
- **RNA Polymerase I - Small Nuclear RNA**

### Conclusion
The wrong pair is **RNA Polymerase I - Small Nuclear RNA**.