If the sequence of bases in the coding strand of a double stranded DNA is 5' -GTTCGAGTC-3' , the sequence of bases in its transcript will be `:`

Options

A. 5’-GACUCGAAC-3’
B. 5’-CAAGCUCAG-3’
C. 5’ –GUUCGAGUC-3’
D. 5’-CUGAGCUUG-3’

Answer

To determine the sequence of bases in the transcript (mRNA) from the given coding strand of DNA, we can follow these steps:

### Step-by-Step Solution:

1. **Identify the Coding Strand**:
The coding strand of the DNA is given as:
\[ 5' - GTTCGAGTC - 3' \]

2. **Understand Transcription**:
During transcription, the DNA coding strand is used as a template to synthesize mRNA. The mRNA is complementary to the DNA template strand and is synthesized in the 5' to 3' direction.

3. **Complementary Base Pairing**:
In RNA, the base pairing rules are:
- Adenine (A) pairs with Uracil (U) instead of Thymine (T).
- Thymine (T) pairs with Adenine (A).
- Cytosine (C) pairs with Guanine (G).
- Guanine (G) pairs with Cytosine (C).

4. **Transcribe the Coding Strand**:
We will now transcribe the coding strand into mRNA by replacing each base according to the rules above:
- G → C
- T → A
- T → A
- C → G
- G → C
- A → U
- G → C
- T → A
- C → G

5. **Write the mRNA Sequence**:
Following the transcription process, the resulting mRNA sequence will be:
\[ 5' - CAA GCU CAG - 3' \]

### Final Answer:
The sequence of bases in its transcript (mRNA) will be:
\[ 5' - CAA GCU CAG - 3' \]