____ gives origin to the skeletal system

Options

A. Endoderm
B. mesoderm
C. Ectoderm
D. Ectoderm and Endoderm

Explanation

To solve the question "____ gives origin to the skeletal system," we need to identify which germ layer is responsible for the development of the skeletal system in humans.

### Step-by-Step Solution:

1. **Understanding Germ Layers**: In human embryonic development, there are three primary germ layers: endoderm, mesoderm, and ectoderm. Each of these layers gives rise to different tissues and organs in the body.

2. **Identifying the Germ Layers**:
- **Endoderm**: This layer primarily forms the epithelial linings of the digestive and respiratory tracts, as well as organs such as the liver and pancreas.
- **Mesoderm**: This layer is responsible for forming various systems, including the skeletal system, muscular system, and reproductive system (excluding germ cells).
- **Ectoderm**: This layer gives rise to the nervous system, skin (epidermis), and structures like the enamel of teeth.

3. **Focusing on the Skeletal System**: The skeletal system is a complex structure that includes bones, cartilage, and connective tissues. According to embryonic development, the skeletal system originates from the mesoderm.

4. **Conclusion**: Based on the information gathered, the correct answer to the question is **mesoderm**.

### Final Answer:
**Mesoderm gives origin to the skeletal system.**

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