Arrange them of the basis of increasing size:

Options

A. Nucleotide, chromosome, gene, genome
B. Genome, chromosomee, nucleotide, gene
C. Nucleotide, genome, gene, chromosome
D. Nucleotide, gene, chromosome, genome

Answer

To arrange the given biological entities in order of increasing size, we need to understand the hierarchy of genetic material. Here’s a step-by-step breakdown:

### Step 1: Identify the smallest unit
The smallest unit in the hierarchy is the **nucleotide**. Nucleotides are the building blocks of nucleic acids (DNA and RNA) and consist of a nitrogenous base, a sugar, and a phosphate group.

**Hint:** Think of nucleotides as the basic units that make up larger structures.

### Step 2: Move to the next level
The next level up from nucleotides is the **gene**. A gene is a segment of DNA that encodes for a specific protein or function. Genes are made up of sequences of nucleotides.

**Hint:** Remember that genes are composed of multiple nucleotides.

### Step 3: Continue to the next level
Next, we have **chromosomes**. Chromosomes are structures within cells that contain many genes. They are made up of tightly coiled DNA and proteins. In humans, for example, there are 46 chromosomes.

**Hint:** Think of chromosomes as packages that contain many genes.

### Step 4: Identify the largest unit
Finally, the largest unit is the **genome**. The genome is the complete set of genetic material in an organism, including all of its chromosomes. In humans, the genome consists of approximately 3 billion base pairs across 46 chromosomes.

**Hint:** The genome encompasses all the genetic information, including all chromosomes.

### Final Arrangement
Now, we can arrange these entities in order of increasing size:
1. Nucleotide
2. Gene
3. Chromosome
4. Genome

### Conclusion
The correct order of increasing size is:
- Nucleotide
- Gene
- Chromosome
- Genome

### Answer
The correct option is: **Nucleotide, Gene, Chromosome, Genome.**