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Assertion : Phenylketonuria, Haemophilia...

Assertion : Phenylketonuria, Haemophilia and sickle cell anemia are genetic disorders.
Reason : In phenylketonuria the person has a non-functional enzyme for the conversion of phenylalanine to tyrosine.

A

Both assertion and reason are true and reason is the correct explanation of the assertion

B

Both assertion and reason are true but reason is not the correct explanation of the assertion

C

Assertion is true but reason is false

D

Both assertion and reason are false

Text Solution

AI Generated Solution

The correct Answer is:
To solve the question, we need to analyze both the assertion and the reason provided. ### Step 1: Analyze the Assertion The assertion states that "Phenylketonuria, Haemophilia, and sickle cell anemia are genetic disorders." - **Phenylketonuria (PKU)** is indeed a genetic disorder caused by a mutation in the gene responsible for producing the enzyme phenylalanine hydroxylase, which is necessary for converting phenylalanine to tyrosine. - **Haemophilia** is a genetic disorder that affects blood clotting, typically inherited in an X-linked recessive manner. - **Sickle cell anemia** is also a genetic disorder caused by a mutation in the hemoglobin gene, leading to abnormal red blood cell shape. Thus, the assertion is true. ### Step 2: Analyze the Reason The reason states that "In phenylketonuria, the person has a non-functional enzyme for the conversion of phenylalanine to tyrosine." - This statement is true because individuals with PKU lack the enzyme phenylalanine hydroxylase, which is responsible for this conversion. As a result, phenylalanine accumulates in the body, leading to various health issues. ### Step 3: Determine the Relationship Now we need to determine if the reason is the correct explanation for the assertion. - While both the assertion and reason are true, the reason specifically pertains to phenylketonuria and does not explain why haemophilia and sickle cell anemia are also classified as genetic disorders. Therefore, the reason does not serve as a correct explanation for the assertion as a whole. ### Conclusion Both the assertion and reason are true, but the reason is not the correct explanation for the assertion. ### Final Answer Both assertion and reason are true, but reason is not the correct explanation of the assertion. ---
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