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Write brief notes on the Cosmid ....

Write brief notes on the Cosmid .

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Cosmid (cos + plasmid) vectors The term cosmid is a combination of two words. COS + MID. COS is taken from COS site of Lambda phage and MID is taken from plasmid DNA. Cosmid was developed for the first time by Collins and Honn (1978). The simplest cosmid vector contains a plasmid.s origin of replication, a selectable marker, suitable restriction enzyme sites and the lambda .cos. site. Cosmids can be used to clone DNA fragments of upto 45 kb length.
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