In patient suffering from malaria, the cells having Schuffner's granules are

Options

A. Gametocytes
B. Signet ring trophozoites
C. Infected red blood cells
D. Infect liver cells.

Answer

To answer the question regarding which cells in patients suffering from malaria contain Schuffner's granules, we can follow these steps:

### Step-by-Step Solution:

1. **Understand Malaria and Its Causative Agent**:
- Malaria is caused by the Plasmodium species, with Plasmodium vivax being the most common. This parasite is transmitted through the bite of infected female Anopheles mosquitoes.

2. **Life Cycle of Plasmodium**:
- The infective stage of Plasmodium vivax is the sporozoite, which enters the human bloodstream after a mosquito bite.

3. **Infection of Liver Cells**:
- Once in the bloodstream, the sporozoites travel to the liver, where they undergo asexual reproduction and multiply.

4. **Invasion of Red Blood Cells (RBCs)**:
- After multiplying in the liver, the next stage involves the invasion of red blood cells (RBCs).

5. **Stages of Development in RBCs**:
- Within the RBCs, the Plasmodium vivax goes through several developmental stages:
- **Trophozoite Stage**: The parasite grows in size by consuming the cytoplasm of the RBCs.
- **Signet Ring Stage**: A contractile vacuole forms, pushing the cytoplasm to one side.
- **Amoeboid Stage**: The parasite continues to develop, and at this stage, Schuffner's granules appear.

6. **Identification of Schuffner's Granules**:
- Schuffner's granules are yellow to orange-colored granules that appear in the cytoplasm of infected RBCs. Their exact chemical nature is still not fully understood.

7. **Conclusion**:
- Therefore, the cells that contain Schuffner's granules in patients suffering from malaria are the infected red blood cells (RBCs).

### Final Answer:
The cells having Schuffner's granules in patients suffering from malaria are the **infected red blood cells (RBCs)**.

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