One of the following is less resistant or more susceptible to antibiotics

Options

A. Gram positive bacteria
B. Gram negative bacteria
C. Escherichia coli
D. None of these.

Answer

### Step-by-Step Solution:

1. **Understand the Question**: The question asks which of the given options is less resistant or more susceptible to antibiotics. This means we need to identify which type of bacteria is more likely to be affected by antibiotics.

2. **Analyze the Options**: The options provided are:
- Option 1: Gram positive bacteria
- Option 2: Gram negative bacteria
- Option 3: Escherichia coli (E. coli)
- Option 4: None of these

3. **Evaluate Gram Positive Bacteria**:
- Gram positive bacteria have a thick peptidoglycan layer and lack an outer membrane, specifically the lipopolysaccharide (LPS) membrane.
- The absence of the outer membrane makes them more susceptible to antibiotics because antibiotics can easily penetrate their cell wall.

4. **Evaluate Gram Negative Bacteria**:
- Gram negative bacteria possess an outer membrane that contains lipopolysaccharides (LPS).
- This outer membrane acts as a barrier, making it more difficult for antibiotics to penetrate the cell, thus rendering them more resistant to antibiotics.

5. **Evaluate Escherichia coli (E. coli)**:
- E. coli is classified as a gram negative bacterium.
- Since it has the protective outer membrane characteristic of gram negative bacteria, it is also resistant to antibiotics.

6. **Consider the Option "None of These"**:
- Since we have already identified a correct answer (gram positive bacteria), the option "none of these" is incorrect.

7. **Conclusion**: Based on the analysis, the bacteria that is less resistant or more susceptible to antibiotics is **Option 1: Gram positive bacteria**.

### Final Answer:
**The correct option is: Gram positive bacteria (Option 1)**.