Single stranded DNA as genetic material in `phixx174` was discovered by

Options

A. Delbruck
B. Safferman and Morris
C. Reed and Finley
D. Sanger

Answer

**Step-by-Step Solution:**

1. **Understanding the Question**: The question asks who discovered that single-stranded DNA serves as genetic material in the bacteriophage φX174.

2. **Identifying the Options**: The options provided are:
- A) Delbruck
- B) Sefferman and Morris
- C) Reed and Finlay
- D) Sanger

3. **Analyzing Each Option**:
- **Delbruck**: He studied bacteria and their mutations related to bacteriophages but did not discover single-stranded DNA in φX174.
- **Sefferman and Morris**: They worked on cyanophages, which are viruses that infect cyanobacteria, not on φX174.
- **Reed and Finlay**: They researched yellow fever transmission by mosquitoes, which is unrelated to φX174.
- **Sanger**: Fred Sanger is known for sequencing the genome of φX174 and discovering that it contains single-stranded DNA as its genetic material.

4. **Conclusion**: Based on the analysis, the correct answer is option D) Sanger, as he was the scientist who discovered that single-stranded DNA is the genetic material in φX174.

5. **Final Answer**: The discovery of single-stranded DNA as genetic material in φX174 was made by Fred Sanger.

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