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The major product H of the given reactio...

The major product `H` of the given reaction sequence is
`CH_(3) - CH_(2) CO - CH_(3) overset (Theta_(CN)) to G - overset (95% H_(2) SO_(4)) underset (Heat) to H`

A

`CH_(3)-CH=underset(CH_(3))underset(|)(C)-COOH`

B

`CH_(3)-CH=underset(CH_(3))underset(|)(C)-CN`

C

`CH_(3)-CH_(2)-underset(CH_(3))underset(|)overset(OH)overset(|)(C)-COOH`

D

`CH_(3)-CH=underset(CH_(3))underset(|)(C)-CO-NH_(2)`

Text Solution

AI Generated Solution

The correct Answer is:
To solve the question regarding the major product \( H \) of the given reaction sequence, we will break down the steps involved in the reaction of ethyl-methyl ketone with cyanide ion and subsequent treatment with sulfuric acid. ### Step-by-Step Solution: 1. **Identify the Starting Compound:** The starting compound is ethyl-methyl ketone, which has the structure: \[ CH_3 - CH_2 - CO - CH_3 \] This compound can also be represented as \( C_4H_8O \). **Hint:** Recognize the structure of the ketone and its components. 2. **Nucleophilic Addition Reaction:** The ketone reacts with the cyanide ion (\( CN^- \)). In this reaction, the cyanide ion acts as a nucleophile and attacks the electrophilic carbon of the carbonyl group (C=O). This leads to the formation of a tetrahedral intermediate: \[ CH_3 - CH_2 - C(OH)(CN) - CH_3 \] After the nucleophilic attack, the oxygen carries a negative charge. **Hint:** Remember that nucleophiles attack electrophilic centers in carbonyl compounds. 3. **Protonation of the Intermediate:** The negatively charged oxygen in the intermediate will then pick up a proton from water or HCN, resulting in the formation of a cyanohydrin: \[ CH_3 - CH_2 - C(OH) - CH_3 - CN \] This compound is known as a cyanohydrin. **Hint:** The formation of cyanohydrin involves protonation of the oxygen atom. 4. **Hydrolysis of the Cyanohydrin:** The cyanohydrin undergoes hydrolysis when treated with 95% sulfuric acid (\( H_2SO_4 \)). The acidic conditions facilitate the conversion of the cyanohydrin into an alpha-hydroxy carboxylic acid: \[ CH_3 - CH_2 - C(OH) - CH_3 - COOH \] This reaction effectively converts the cyanide group into a carboxylic acid group. **Hint:** Hydrolysis in acidic conditions transforms cyanohydrins into carboxylic acids. 5. **Final Product:** The final product \( H \) is an alpha-hydroxy carboxylic acid with the structure: \[ CH_3 - CH_2 - C(OH) - CH_3 - COOH \] This compound is known as 3-hydroxybutanoic acid. **Hint:** Identify the functional groups in the final product to confirm the structure. ### Conclusion: The major product \( H \) of the given reaction sequence is 3-hydroxybutanoic acid. ### Answer: The correct answer is option 3 (3-hydroxybutanoic acid).

To solve the question regarding the major product \( H \) of the given reaction sequence, we will break down the steps involved in the reaction of ethyl-methyl ketone with cyanide ion and subsequent treatment with sulfuric acid. ### Step-by-Step Solution: 1. **Identify the Starting Compound:** The starting compound is ethyl-methyl ketone, which has the structure: \[ CH_3 - CH_2 - CO - CH_3 ...
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