Agranulocytes normally develop in

Options

A. Bone marrow
B. Liver
C. Lymph glands and spleen
D. None of these.

Answer

### Step-by-Step Text Solution:

1. **Understanding Agranulocytes**: Agranulocytes are a type of white blood cell (WBC) that do not contain granules in their cytoplasm. They are part of the immune system and play a crucial role in the body's defense mechanism.

2. **Types of Agranulocytes**: The two main types of agranulocytes are:
- **Lymphocytes**: These include B cells and T cells.
- **Monocytes**: These cells can differentiate into macrophages and dendritic cells.

3. **Development of Agranulocytes**:
- **Hematopoiesis**: The process of blood cell formation is known as hematopoiesis. Agranulocytes are derived from hematopoietic stem cells.
- **Bone Marrow**: Initially, agranulocytes, particularly lymphocytes, are produced in the bone marrow.
- **Secondary Lymphoid Organs**: After their initial development in the bone marrow, lymphocytes mature in secondary lymphoid organs, which include lymph glands (lymph nodes) and the spleen.

4. **Analyzing the Options**:
- **Bone Marrow**: This is where the initial development of agranulocytes occurs, but it is not where they fully mature.
- **Liver**: This is not involved in the development of agranulocytes.
- **Lymph Glands**: This is where lymphocytes mature, making it a correct option.
- **Spleen**: Similar to lymph glands, it is also involved in the maturation of lymphocytes.
- **None of these**: This option is incorrect as lymph glands and spleen are valid sites for agranulocyte development.

5. **Conclusion**: The correct answer to the question "Agranulocytes normally develop in" is **lymph glands** and **spleen**, as these are secondary lymphoid organs where lymphocytes mature.