What is the proper sequence in mitosis ?

Options

A. Metaphase, telophase, prophase and anaphase
B. Prophase, metaphase, anaphase and telophase
C. Anaphase, metaphase, telophase and prophase
D. Telophase, anaphase, metaphase and prophase

Answer

**Step-by-Step Text Solution:**

1. **Understanding Mitosis**: Mitosis is a type of cell division that results in two daughter cells, each having the same number of chromosomes as the parent cell. It is essential for growth, development, and tissue repair.

2. **Phases of Mitosis**: Mitosis consists of four main phases:
- **Prophase**: This is the first phase of mitosis. During prophase, the chromatin condenses into visible chromosomes, and the nuclear membrane begins to break down. The spindle fibers also start to form.

- **Metaphase**: In this second phase, the chromosomes align at the equatorial plane (also known as the metaphase plate) of the cell. This alignment is crucial for the equal distribution of chromosomes to the daughter cells.

- **Anaphase**: During anaphase, the sister chromatids (which are identical copies of a chromosome) are pulled apart towards opposite poles of the cell. This ensures that each daughter cell will receive an identical set of chromosomes.

- **Telophase**: The final phase of mitosis is telophase. Here, the chromosomes reach the opposite poles and begin to de-condense back into chromatin. The nuclear membrane re-forms around each set of chromosomes, resulting in the formation of two distinct nuclei.

3. **Final Sequence**: The proper sequence of the phases in mitosis is:
- Prophase
- Metaphase
- Anaphase
- Telophase

Thus, the correct answer to the question is: **Prophase, Metaphase, Anaphase, Telophase**.

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