Chromosomes separate during

Options

A. Early prophase
B. Early metaphase
C. Early anaphase
D. Early telophase

Answer

**Step-by-Step Solution:**

1. **Understanding the Question**: The question asks during which phase of cell division chromosomes separate.

2. **Evaluating Early Prophase**: In early prophase, chromosomes condense and the nuclear membrane disintegrates, but the chromosomes do not separate at this stage. Therefore, early prophase is not the correct answer.

3. **Evaluating Metaphase**: During metaphase, chromosomes align at the equatorial plane of the cell. They are not separating at this stage either. Thus, metaphase is also not the correct answer.

4. **Evaluating Anaphase**: Anaphase is the stage where the centromeres that hold sister chromatids together split, allowing the sister chromatids to move apart towards opposite poles of the cell. This is the phase where chromosome separation occurs.

5. **Evaluating Early Telophase**: In early telophase, the separated chromatids reach the poles of the cell and begin to uncoil. This stage does not involve the separation of chromosomes, so it is not the correct answer.

6. **Conclusion**: The correct answer to the question "Chromosomes separate during" is **Anaphase**.