`G_(0)` state of cell denotes

Options

A. Exit of cell from cell cycle
B. Check point before entering next phase
C. Death of cell
D. Temporary pause/suspended cell cycle

Answer

To answer the question about what the G0 state of a cell denotes, we can break down the information as follows:

### Step-by-Step Solution:

1. **Understanding the Cell Cycle**: The cell cycle consists of several phases: G1, S, G2, and M (mitotic phase). Each phase has specific functions related to cell growth, DNA replication, and cell division.

2. **Identifying the G0 Phase**: After the M phase, a cell can either continue to divide or enter a resting state known as the G0 phase. This phase is often referred to as the quiescent stage.

3. **Characteristics of the G0 Phase**:
- In the G0 phase, the cell is not actively preparing to divide.
- Cells in this phase may exit the cell cycle temporarily or permanently, depending on the type of cell and its environment.
- Some cells, like certain nerve cells, remain in the G0 phase for an extended period, effectively being in a resting state.

4. **Options Analysis**:
- **Exit of cell from cell cycle**: This accurately describes the G0 phase, as cells can exit the cycle and enter this resting state.
- **Checkpoint before entering next phase**: This refers to the G1 and G2 checkpoints, not the G0 phase.
- **Death of cell**: This is related to apoptosis or necrosis, which is not what the G0 phase represents.
- **Temporary pause or suspended cell cycle**: While this might seem correct, the G0 phase is more accurately described as an exit from the cycle rather than a temporary pause.

5. **Conclusion**: The G0 state of a cell denotes the exit of the cell from the cell cycle, making option A the correct answer.

### Final Answer:
The G0 state of a cell denotes the **exit of the cell from the cell cycle**.

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