During meiosis

Options

A. Linkage is disturbed
B. Homologous chromosomes are separated
C. Homologous chromosomes do not segregate
D. All the above

Answer

**Step-by-Step Solution:**

1. **Understanding Meiosis:**
- Meiosis is a type of cell division that reduces the chromosome number by half, resulting in four daughter cells, each with half the number of chromosomes of the parent cell. This is also referred to as reductional division.

2. **Phases of Meiosis:**
- Meiosis consists of two main phases: Meiosis I and Meiosis II. The key event in Meiosis I is the separation of homologous chromosomes.

3. **Homologous Chromosome Separation:**
- During Meiosis I, specifically in Anaphase I, homologous chromosomes are separated and pulled to opposite poles of the cell. This is crucial for ensuring that each daughter cell receives only one chromosome from each homologous pair.

4. **Evaluating the Options:**
- **Option A: Linkage is disturbed.**
- This is incorrect. Linkage refers to the tendency of genes located close together on a chromosome to be inherited together. It is not directly affected by meiosis.
- **Option B: Homologous chromosomes are separated.**
- This is correct. The primary function of Meiosis I is to separate homologous chromosomes.
- **Option C: Homologous chromosomes don't segregate.**
- This is incorrect. The essence of meiosis is the segregation of homologous chromosomes.
- **Option D: All of the above.**
- This is also incorrect since not all statements are true.

5. **Conclusion:**
- The correct answer is **Option B: Homologous chromosomes are separated.**