The major event that occurs during the anaphase of mitosis. Which bring about the equal distribution of chromosomes, is

Options

A. Splitting of centromeres
B. Condensation of chromatin
C. Replication of genetic material
D. Splitting of chromatids.

Answer

**Step-by-Step Solution:**

1. **Understanding Anaphase**: Anaphase is a stage in mitosis, which is the process of cell division. It follows metaphase and precedes telophase. During anaphase, the cell ensures that each daughter cell will receive an identical set of chromosomes.

2. **Key Event in Anaphase**: The major event that occurs during anaphase is the separation of sister chromatids. Each chromosome is made up of two identical halves, known as sister chromatids, which are joined together at a region called the centromere.

3. **Splitting of Centromeres**: The centromere is the part of the chromosome that holds the two sister chromatids together. During anaphase, the centromeres split, allowing the sister chromatids to separate and move towards opposite poles of the cell.

4. **Formation of Daughter Chromosomes**: Once the sister chromatids are separated, they are referred to as daughter chromosomes. This ensures that each new daughter cell will have the same number of chromosomes as the original cell.

5. **Conclusion**: Therefore, the major event that occurs during the anaphase of mitosis, which brings about the equal distribution of chromosomes, is the splitting of centromeres.

**Final Answer**: The major event that occurs during the anaphase of mitosis, which brings about the equal distribution of chromosomes, is the splitting of centromeres.

---