The homologous genes are separated at

Options

A. Anaphase I
B. Pachytene
C. Diplotene
D. Anaphase II

Answer

**Step-by-Step Solution:**

1. **Understanding Homologous Genes:**
Homologous genes are genes that are located on homologous chromosomes, which are pairs of chromosomes that have the same structure and carry the same genes but may have different alleles.

2. **Identifying the Process of Separation:**
The separation of homologous genes occurs during meiosis, specifically in the first meiotic division (meiosis I).

3. **Meiosis I Stages:**
- Meiosis I consists of several stages: prophase I, metaphase I, anaphase I, and telophase I.
- During prophase I, homologous chromosomes pair up and exchange genetic material through a process called crossing over.

4. **Key Stage for Separation:**
- The actual separation of homologous chromosomes occurs during **anaphase I** of meiosis I.
- In this stage, the homologous chromosomes are pulled apart towards opposite poles of the cell.

5. **Role of Enzymes:**
- The enzyme separase plays a crucial role in this process by cleaving the cohesin proteins that hold the homologous chromosomes together, allowing them to separate.

6. **Conclusion:**
- Therefore, the correct answer to the question "The homologous genes are separated at" is **anaphase I** of meiosis I.

**Final Answer: Anaphase I of meiosis I.**

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