Spindle can be observed best under

Options

A. Light microscope
B. Polarising microscope
C. Phase contrast microscope
D. Interference microscope

Explanation

To determine the best microscope for observing the spindle, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Structure of the Spindle**:
- The spindle is a structure made of microtubules that plays a crucial role in cell division by helping to segregate genetic material.

2. **Identify the Properties of the Spindle**:
- Spindles exhibit anisotropic properties, meaning their optical characteristics depend on the direction of observation.

3. **Consider the Types of Microscopes**:
- **Light Microscope**: Generally used for observing living cells but may not provide the best resolution for spindle structures.
- **Polarizing Microscope**: Specifically designed to observe structures with anisotropic properties using plane polarized light.
- **Phase Contrast Microscope**: Enhances contrast in transparent specimens but is not specifically tailored for anisotropic materials.
- **Interference Microscope**: Used for measuring small thicknesses and refractive index changes but is not ideal for spindle observation.

4. **Evaluate the Best Option**:
- Given that spindles have anisotropic properties, the polarizing microscope is the most suitable choice as it utilizes polarizers and analyzers to study these structures effectively.

5. **Conclusion**:
- The best microscope to observe spindle structures is the **polarizing microscope**.

### Final Answer:
The spindle can be observed best under a **polarizing microscope**.

---