Glycolysis and TCA cycle operate respectively in

Options

A. Cytosol and matrix of mitochondrion
B. Cytosol and stroma of chloroplast
C. Cytosol and oxysomes of mitochondrion
D. Matrix of mitochondrion and inner membrane of mitochondrion.

Answer

**Step-by-Step Solution:**

1. **Understanding Glycolysis:**
- Glycolysis is the metabolic pathway that breaks down glucose into pyruvate.
- It is a crucial step in both aerobic and anaerobic respiration.
- Glycolysis occurs in the cytoplasm (or cytosol) of the cell, which is present in both prokaryotic and eukaryotic organisms.

2. **Understanding the TCA Cycle:**
- The TCA cycle, also known as the Krebs cycle or tricarboxylic acid cycle, is a series of reactions that occur after glycolysis.
- This cycle is strictly an aerobic process, meaning it requires oxygen to proceed.
- The TCA cycle occurs in the matrix of the mitochondria in eukaryotic cells. Prokaryotic cells do not have mitochondria, so they do not perform the TCA cycle.

3. **Evaluating the Options:**
- Option A: Cytosol and matrix of mitochondria – This is correct as glycolysis occurs in the cytosol and the TCA cycle occurs in the matrix of mitochondria.
- Option B: Cytosol and stroma of chloroplast – Incorrect, as the TCA cycle does not occur in the chloroplast; that space is involved in the Calvin cycle.
- Option C: Cytosol and auxosomes of mitochondria – Incorrect, as auxosomes are not a recognized term in this context.
- Option D: Matrix of mitochondria and inner membrane of mitochondria – Incorrect, as oxidative phosphorylation occurs in the inner membrane, not the TCA cycle.

4. **Conclusion:**
- The correct answer is Option A: Glycolysis operates in the cytosol, and the TCA cycle operates in the matrix of mitochondria.