In glycolysis, 6-C compounds are split into 3-C compounds by enzyme

Options

A. Isomerase
B. Aldolase
C. Hexokinase
D. Dehydrogenase.

Answer

**Step-by-Step Solution:**

1. **Understanding Glycolysis**: Glycolysis is a metabolic pathway that converts glucose (a 6-carbon compound) into pyruvate (a 3-carbon compound). This process occurs in the cytoplasm of the cell and involves several enzymatic reactions.

2. **Identifying the Reaction**: In glycolysis, one of the key steps involves the splitting of a 6-carbon compound, specifically fructose 1,6-bisphosphate, into two 3-carbon molecules: glyceraldehyde 3-phosphate (G3P) and dihydroxyacetone phosphate (DHAP).

3. **Enzyme Involved**: The enzyme responsible for this splitting reaction is called aldolase. It catalyzes the cleavage of fructose 1,6-bisphosphate into G3P and DHAP.

4. **Reviewing Other Options**:
- **Isomerase**: This enzyme converts glucose 6-phosphate into its isomer, fructose 6-phosphate, but does not split 6-carbon compounds.
- **Hexokinase**: This enzyme catalyzes the phosphorylation of glucose to glucose 6-phosphate at the beginning of glycolysis.
- **Dehydrogenase**: This enzyme is involved in the removal of hydrogen ions and electrons from intermediates but does not split 6-carbon compounds.

5. **Conclusion**: Based on the above analysis, the correct enzyme that splits the 6-carbon compound into 3-carbon compounds in glycolysis is **aldolase**.

**Final Answer**: Aldolase

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