Which one is the first compound which is common for both glucose and fructose in glycolysis

Options

A. Fructose 6-P
B. Glucose 6-P
C. Fructose 1,6-biphosphate
D. Fructose 1-P.

Answer

To answer the question "Which one is the first compound which is common for both glucose and fructose in glycolysis?", we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Glycolysis**: Glycolysis is the metabolic pathway that converts glucose into pyruvate, producing ATP and NADH in the process. It consists of several steps, starting with the phosphorylation of glucose.

2. **Glucose Metabolism**: When glucose enters glycolysis, it is phosphorylated by the enzyme hexokinase to form glucose 6-phosphate (G6P). This is the first step in the glycolytic pathway for glucose.

3. **Fructose Metabolism**: Fructose can also enter the glycolytic pathway. It is converted into fructose 6-phosphate (F6P) by the enzyme phosphofructokinase. This conversion allows fructose to enter glycolysis at a similar point as glucose.

4. **Identifying Common Intermediate**: Both glucose and fructose are converted into fructose 6-phosphate (F6P) during glycolysis. This compound serves as a common intermediate for both sugars.

5. **Conclusion**: The first compound that is common for both glucose and fructose in glycolysis is fructose 6-phosphate.

### Final Answer:
**Fructose 6-phosphate** is the first compound that is common for both glucose and fructose in glycolysis.

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