Which of the two statements together support that respiratory pathway is an amphibolic pathway ,
(i) Fats breakdown to glycerol and fatty acids, subsequently yields acetyl CoA
(ii) In respiration C-C bonds of complex compounds breakdown through oxidation leading to release of energy
(iii) Acetyl CoA from respiratory pathway is withdrawn for synthesis of fatty acids
(iv) Proteins are degraded by protease to amino acids and enter the respiratory pathway

Options

A. I, ii
B. I, iv
C. ii, iv
D. ii, iii

Answer

To determine which two statements support the idea that the respiratory pathway is an amphibolic pathway, we need to understand what an amphibolic pathway is. An amphibolic pathway is one that involves both catabolic (breaking down molecules) and anabolic (building up molecules) processes.

### Step-by-Step Solution:

1. **Understanding the Statements**:
- **Statement (i)**: Fats break down to glycerol and fatty acids, subsequently yielding acetyl CoA.
- **Statement (ii)**: In respiration, C-C bonds of complex compounds break down through oxidation leading to the release of energy.
- **Statement (iii)**: Acetyl CoA from the respiratory pathway is withdrawn for the synthesis of fatty acids.
- **Statement (iv)**: Proteins are degraded by protease to amino acids and enter the respiratory pathway.

2. **Analyzing Each Statement**:
- **Statement (i)** indicates that fats can be broken down into components that yield acetyl CoA, which can then enter the Krebs cycle. This shows a catabolic process (breaking down fats) and suggests that intermediates can be used in other pathways.
- **Statement (ii)** describes the breakdown of complex compounds to release energy, which is a purely catabolic process. It does not indicate any anabolic function and thus does not support the amphibolic nature.
- **Statement (iii)** states that acetyl CoA can be used for the synthesis of fatty acids, indicating an anabolic process. This shows that the respiratory pathway can also contribute to building larger molecules.
- **Statement (iv)** explains that proteins can be broken down into amino acids, which can then enter the respiratory pathway. This indicates that the respiratory pathway can also utilize components from protein metabolism, showing both catabolic and anabolic functions.

3. **Identifying Supporting Statements**:
- From the analysis, **Statements (i)** and **(iv)** together support the idea that the respiratory pathway is amphibolic. Statement (i) shows the catabolic aspect (breakdown of fats) while Statement (iv) shows the anabolic aspect (utilization of amino acids).

4. **Conclusion**:
- The two statements that support that the respiratory pathway is an amphibolic pathway are **(i)** and **(iv)**.

### Final Answer:
The correct statements that support the respiratory pathway as an amphibolic pathway are **(i)** and **(iv)**.

---