The elimination of insoluble calcium phosphate takes place by

Options

A. Liver
B. Kidney
C. Larger intestine
D. Skin

Answer

To solve the question regarding the elimination of insoluble calcium phosphate, we can follow these steps:

### Step-by-Step Solution:

1. **Identify the Substance**: The question mentions "insoluble calcium phosphate." This is a salt that is not soluble in water.

2. **Understand Absorption**: Calcium phosphate is absorbed by the cells of the intestine as per the body's requirements. This means that the body takes in what it needs, but there may be excess that needs to be eliminated.

3. **Determine Elimination Pathways**: Since calcium phosphate is insoluble, it cannot be excreted through urine, which is the primary function of the kidneys. Therefore, we need to look for another pathway for elimination.

4. **Consider the Options**: The options given are:
- Liver
- Kidney
- Large intestine
- Skin

5. **Evaluate Each Option**:
- **Liver**: The liver is involved in metabolism and detoxification but does not excrete calcium phosphate.
- **Kidney**: The kidneys filter blood and excrete soluble substances as urine. Since calcium phosphate is insoluble, it cannot be eliminated through the kidneys.
- **Large Intestine**: The large intestine is responsible for the elimination of solid waste. Insoluble substances that are not absorbed by the body can be excreted in feces.
- **Skin**: The skin primarily excretes sweat and does not play a role in the elimination of calcium phosphate.

6. **Conclusion**: Based on the evaluation, the correct answer is the large intestine, as it is responsible for the elimination of insoluble calcium phosphate in the form of feces.

### Final Answer:
The elimination of insoluble calcium phosphate takes place by the **large intestine**.

---