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Assertion. In PCT, glomerular filtrate b...

Assertion. In PCT, glomerular filtrate becomes hypertoinc
Reason. `HCO_(3)` is absorbed in PCT

A

both are true with reason being correct explanation

B

both are true but reason is not correct explanation

C

assertion is true but reason is wrong

D

both are wrong

Text Solution

AI Generated Solution

The correct Answer is:
To solve the assertion and reason question regarding the proximal convoluted tubule (PCT) and bicarbonate (HCO₃) absorption, we will analyze both statements step by step. ### Step-by-Step Solution: 1. **Understanding the Assertion:** - The assertion states that in the PCT, the glomerular filtrate becomes hypertonic. - The PCT is responsible for the reabsorption of various substances from the filtrate back into the blood. - In the PCT, the majority of water and solutes (like glucose, amino acids, and ions) are reabsorbed. - As a result of this reabsorption, the osmolarity of the filtrate becomes similar to that of the blood plasma, making it isotonic rather than hypertonic. 2. **Conclusion on the Assertion:** - Since the assertion claims that the filtrate becomes hypertonic, which contradicts the fact that it becomes isotonic due to reabsorption, the assertion is **false**. 3. **Understanding the Reason:** - The reason states that HCO₃ (bicarbonate) is absorbed in the PCT. - While bicarbonate is indeed involved in acid-base balance and is reabsorbed in the kidneys, the majority of bicarbonate reabsorption occurs in the proximal tubule. - However, the statement as presented does not specify the extent or correctness of this absorption, leading to ambiguity. 4. **Conclusion on the Reason:** - Although bicarbonate is reabsorbed in the PCT, the assertion is primarily concerned with the hypertonicity of the filtrate. Therefore, while the reason may have some truth, it does not correctly explain the assertion. - Thus, the reason can be considered **true**, but it does not support the assertion. 5. **Final Conclusion:** - The assertion is **false**, and the reason is **true**. Therefore, the correct answer is that both statements are not correct in relation to each other.
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