Choose the wrong statement regarding urine formation

Options

A. Filtration is non-selective process perfomed by glomerulus
B. Glomerular capillary blood pressure causes filtration of blood through three layers
C. GFR in a healty individual is approximately 125 ml/min
D. Ascending limb of Henle's loop is permeable to water but allows transport of electrolytes actively or passively

Answer

To solve the question "Choose the wrong statement regarding urine formation," we will analyze each option provided and determine which statement is incorrect.

### Step-by-Step Solution:

1. **Understand the Question**: We need to identify the statement that is incorrect regarding the process of urine formation.

2. **Evaluate Each Statement**:
- **Option A**: "Filtration is a non-selective process performed by the glomerulus."
- **Analysis**: This statement is correct. The glomerulus filters blood in a non-selective manner, allowing various substances to pass through.

- **Option B**: "Glomerular capillary blood pressure causes the filtration of blood through three layers."
- **Analysis**: This statement is also correct. The filtration occurs due to the pressure in the glomerular capillaries, and it passes through three layers: two epithelial layers and a basement membrane.

- **Option C**: "The GFR in a healthy individual is approximately 125 ml per minute."
- **Analysis**: This statement is correct as well. The Glomerular Filtration Rate (GFR) in healthy individuals typically ranges from 90 to 125 ml/min.

- **Option D**: "The ascending limb of the Henle's loop is permeable to water."
- **Analysis**: This statement is incorrect. The ascending limb of the loop of Henle is not permeable to water; it is primarily permeable to salts (like NaCl) and allows for the active or passive transport of electrolytes.

3. **Identify the Wrong Statement**: After evaluating all options, we find that Option D is the wrong statement regarding urine formation.

4. **Conclusion**: The answer to the question is Option D.

### Final Answer:
The wrong statement regarding urine formation is: **The ascending limb of the Henle's loop is permeable to water.**

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