Which of the following disease shows the blockage of kidney tubules and causes severe back pain

Options

A. Renal calculi
B. Uremia
C. Kidney failure
D. Nephritis

Answer

### Step-by-Step Solution:

1. **Understanding the Question**: The question asks which disease causes a blockage of kidney tubules and severe back pain. We need to analyze the options provided.

2. **Analyzing the Options**:
- **Renal Calculi**: This condition is commonly known as kidney stones. It occurs when hard deposits of minerals and salts form in the kidneys, leading to blockages in the kidney tubules. Symptoms include severe back pain and difficulty in urination.
- **Uremia**: This condition arises when urea accumulates in the blood due to impaired kidney function. Symptoms include fatigue, loss of appetite, and mental confusion, but it does not specifically cause back pain or blockage of kidney tubules.
- **Kidney Failure**: This refers to a condition where the kidneys fail to filter waste effectively. Symptoms include fatigue and puffiness, but again, it does not specifically mention blockage of kidney tubules or severe back pain.
- **Nephritis**: This is the inflammation of the kidneys, characterized by symptoms like blood and pus in the urine. It does not directly indicate blockage of kidney tubules or severe back pain.

3. **Identifying the Correct Answer**: Based on the analysis, renal calculi (kidney stones) is the only condition that specifically indicates blockage of kidney tubules and is associated with severe back pain.

4. **Conclusion**: The correct answer to the question is **Renal Calculi**.