A nucleated differentiated cell that has lost the power to differentiated cell that has lost the power to dedifferentiate is

Options

A. Nerve cell
B. Kideny cell
C. Liver cell
D. All the above

Answer

To solve the question, "A nucleated differentiated cell that has lost the power to dedifferentiate is:", we will analyze the options provided and the characteristics of the cells mentioned.

### Step-by-Step Solution:

1. **Understanding the Terms**:
- **Nucleated Cell**: This refers to a cell that contains a nucleus. Most eukaryotic cells, including nerve, kidney, and liver cells, are nucleated.
- **Differentiated Cell**: These are cells that have specialized functions and structures. They have developed into specific types of cells (e.g., nerve cells, kidney cells, liver cells).
- **Lost the Power to Dedifferentiate**: This means that the cell can no longer revert to a less specialized form. Dedifferentiation is the process where a differentiated cell can revert to a more stem-like state.

2. **Analyzing the Options**:
- **A. Nerve Cells**: Nerve cells (neurons) are highly specialized and do not typically divide or dedifferentiate. Once they are formed, they maintain their specialized functions and do not revert to a less specialized state.
- **B. Kidney Cells**: Kidney cells are capable of regeneration and can divide to replace damaged cells. They retain the ability to dedifferentiate under certain conditions.
- **C. Liver Cells**: Liver cells (hepatocytes) also have the ability to divide and can dedifferentiate when necessary, especially in response to injury.
- **D. All of the Above**: This option implies that all the mentioned cell types have lost the power to dedifferentiate, which is not accurate.

3. **Conclusion**:
- Based on the analysis, the correct answer is **A. Nerve Cells**. They are nucleated, differentiated cells that have lost the ability to dedifferentiate.

### Final Answer:
**Option A: Nerve Cells**